5CCJ
Crystal structure of the quintuple mutant of the synaptotagmin-1 C2B domain
Summary for 5CCJ
Entry DOI | 10.2210/pdb5ccj/pdb |
Descriptor | Synaptotagmin-1, GLYCEROL, SULFATE ION, ... (4 entities in total) |
Functional Keywords | synaptotagmin1, c2b domain, signaling protein |
Biological source | Rattus norvegicus (Rat) |
Cellular location | Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass membrane protein: P21707 |
Total number of polymer chains | 4 |
Total formula weight | 72671.13 |
Authors | Zhou, Q.,Zhao, M.,Brunger, A.T. (deposition date: 2015-07-02, release date: 2015-08-12, Last modification date: 2023-09-27) |
Primary citation | Zhou, Q.,Lai, Y.,Bacaj, T.,Zhao, M.,Lyubimov, A.Y.,Uervirojnangkoorn, M.,Zeldin, O.B.,Brewster, A.S.,Sauter, N.K.,Cohen, A.E.,Soltis, S.M.,Alonso-Mori, R.,Chollet, M.,Lemke, H.T.,Pfuetzner, R.A.,Choi, U.B.,Weis, W.I.,Diao, J.,Sudhof, T.C.,Brunger, A.T. Architecture of the synaptotagmin-SNARE machinery for neuronal exocytosis. Nature, 525:62-67, 2015 Cited by PubMed: 26280336DOI: 10.1038/nature14975 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.65 Å) |
Structure validation
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