5CCJ

Crystal structure of the quintuple mutant of the synaptotagmin-1 C2B domain

Summary for 5CCJ

Entry DOI	10.2210/pdb5ccj/pdb
Descriptor	Synaptotagmin-1, GLYCEROL, SULFATE ION, ... (4 entities in total)
Functional Keywords	synaptotagmin1, c2b domain, signaling protein
Biological source	Rattus norvegicus (Rat)
Cellular location	Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass membrane protein: P21707
Total number of polymer chains	4
Total formula weight	72671.13
Authors	Zhou, Q.,Zhao, M.,Brunger, A.T. (deposition date: 2015-07-02, release date: 2015-08-12, Last modification date: 2023-09-27)
Primary citation	Zhou, Q.,Lai, Y.,Bacaj, T.,Zhao, M.,Lyubimov, A.Y.,Uervirojnangkoorn, M.,Zeldin, O.B.,Brewster, A.S.,Sauter, N.K.,Cohen, A.E.,Soltis, S.M.,Alonso-Mori, R.,Chollet, M.,Lemke, H.T.,Pfuetzner, R.A.,Choi, U.B.,Weis, W.I.,Diao, J.,Sudhof, T.C.,Brunger, A.T. Architecture of the synaptotagmin-SNARE machinery for neuronal exocytosis. Nature, 525:62-67, 2015 Cited by PubMed: 26280336 DOI: 10.1038/nature14975 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.65 Å)

Structure validation