5CA1

Crystal structure of T2R-TTL-Nocodazole complex

Summary for 5CA1

• Entry DOI: 10.2210/pdb5ca1/pdb
• Related: 5C8Y 5CA0 5CB4
• Descriptor: Tubulin alpha, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, nocodazole, ... (13 entities in total)
• Functional Keywords: inhibitor, complex, tubulin, structural protein
• Biological source: Gallus gallus (Chicken); More
• Cellular location: Cytoplasm, cytoskeleton: P32882; Golgi apparatus : P63043
• Total number of polymer chains: 6
• Total formula weight: 264981.23

Authors

Wang, Y.,Yu, Y.,Chen, Q.,Yang, J. (deposition date: 2015-06-29, release date: 2015-11-04, Last modification date: 2023-11-08)

• Primary citation: Wang, Y.,Zhang, H.,Gigant, B.,Yu, Y.,Wu, Y.,Chen, X.,Lai, Q.,Yang, Z.,Chen, Q.,Yang, J.; Structures of a diverse set of colchicine binding site inhibitors in complex with tubulin provide a rationale for drug discovery.; Febs J., 283:102-111, 2016; PubMed: 26462166; DOI: 10.1111/febs.13555

Experimental method

X-RAY DIFFRACTION (2.401 Å)