5C9J

Human CD1c with ligands in A' and F' channel

Summary for 5C9J

• Entry DOI: 10.2210/pdb5c9j/pdb
• Descriptor: T-cell surface glycoprotein CD1c,T-cell surface glycoprotein CD1b, Beta-2-microglobulin, LAURIC ACID, ... (7 entities in total)
• Functional Keywords: antigen presentation, cd1, human cd1, mhc-like, immunology, lipid antigen, immune system
• Biological source: Homo sapiens (Human); More
• Cellular location: Cell membrane ; Single- pass type I membrane protein : P29016; Secreted : P61769
• Total number of polymer chains: 2
• Total formula weight: 44463.82

Authors

Tews, I.,Machelett, M.M.,Mansour, S.,Gadola, S.D. (deposition date: 2015-06-27, release date: 2016-03-02, Last modification date: 2024-01-10)

• Primary citation: Mansour, S.,Tocheva, A.S.,Cave-Ayland, C.,Machelett, M.M.,Sander, B.,Lissin, N.M.,Molloy, P.E.,Baird, M.S.,Stubs, G.,Schroder, N.W.,Schumann, R.R.,Rademann, J.,Postle, A.D.,Jakobsen, B.K.,Marshall, B.G.,Gosain, R.,Elkington, P.T.,Elliott, T.,Skylaris, C.K.,Essex, J.W.,Tews, I.,Gadola, S.D.; Cholesteryl esters stabilize human CD1c conformations for recognition by self-reactive T cells.; Proc.Natl.Acad.Sci.USA, 113:E1266-E1275, 2016; PubMed: 26884207; DOI: 10.1073/pnas.1519246113

Experimental method

X-RAY DIFFRACTION (2.4 Å)