5C9J
Human CD1c with ligands in A' and F' channel
Summary for 5C9J
Entry DOI | 10.2210/pdb5c9j/pdb |
Descriptor | T-cell surface glycoprotein CD1c,T-cell surface glycoprotein CD1b, Beta-2-microglobulin, LAURIC ACID, ... (7 entities in total) |
Functional Keywords | antigen presentation, cd1, human cd1, mhc-like, immunology, lipid antigen, immune system |
Biological source | Homo sapiens (Human) More |
Cellular location | Cell membrane ; Single- pass type I membrane protein : P29016 Secreted : P61769 |
Total number of polymer chains | 2 |
Total formula weight | 44463.82 |
Authors | Tews, I.,Machelett, M.M.,Mansour, S.,Gadola, S.D. (deposition date: 2015-06-27, release date: 2016-03-02, Last modification date: 2024-01-10) |
Primary citation | Mansour, S.,Tocheva, A.S.,Cave-Ayland, C.,Machelett, M.M.,Sander, B.,Lissin, N.M.,Molloy, P.E.,Baird, M.S.,Stubs, G.,Schroder, N.W.,Schumann, R.R.,Rademann, J.,Postle, A.D.,Jakobsen, B.K.,Marshall, B.G.,Gosain, R.,Elkington, P.T.,Elliott, T.,Skylaris, C.K.,Essex, J.W.,Tews, I.,Gadola, S.D. Cholesteryl esters stabilize human CD1c conformations for recognition by self-reactive T cells. Proc.Natl.Acad.Sci.USA, 113:E1266-E1275, 2016 Cited by PubMed: 26884207DOI: 10.1073/pnas.1519246113 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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