5C9J

Human CD1c with ligands in A' and F' channel

5C9J の概要

• エントリーDOI: 10.2210/pdb5c9j/pdb
• 分子名称: T-cell surface glycoprotein CD1c,T-cell surface glycoprotein CD1b, Beta-2-microglobulin, LAURIC ACID, ... (7 entities in total)
• 機能のキーワード: antigen presentation, cd1, human cd1, mhc-like, immunology, lipid antigen, immune system
• 由来する生物種: Homo sapiens (Human); 詳細
• 細胞内の位置: Cell membrane ; Single- pass type I membrane protein : P29016; Secreted : P61769
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 44463.82

構造登録者

Tews, I.,Machelett, M.M.,Mansour, S.,Gadola, S.D. (登録日: 2015-06-27, 公開日: 2016-03-02, 最終更新日: 2024-01-10)

• 主引用文献: Mansour, S.,Tocheva, A.S.,Cave-Ayland, C.,Machelett, M.M.,Sander, B.,Lissin, N.M.,Molloy, P.E.,Baird, M.S.,Stubs, G.,Schroder, N.W.,Schumann, R.R.,Rademann, J.,Postle, A.D.,Jakobsen, B.K.,Marshall, B.G.,Gosain, R.,Elkington, P.T.,Elliott, T.,Skylaris, C.K.,Essex, J.W.,Tews, I.,Gadola, S.D.; Cholesteryl esters stabilize human CD1c conformations for recognition by self-reactive T cells.; Proc.Natl.Acad.Sci.USA, 113:E1266-E1275, 2016; PubMed: 26884207; DOI: 10.1073/pnas.1519246113

実験手法

X-RAY DIFFRACTION (2.4 Å)