5C8G

Crystal Structure Analysis of PP-BRD20 from Tb427tmp complexed with BI-2536

Summary for 5C8G

• Entry DOI: 10.2210/pdb5c8g/pdb
• Descriptor: PP-BRD20, 4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxy-N-(1-methylpiperidin-4-yl)benzamide, UNKNOWN ATOM OR ION, ... (4 entities in total)
• Functional Keywords: structural genomics consortium, sgc, bromodomain, pp-brd20, tb427tmp, gene regulation
• Biological source: Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)
• Total number of polymer chains: 2
• Total formula weight: 32784.95

Authors

Jiang, D.Q.,Tempel, W.,Loppnau, P.,Graslund, S.,Hou, C.F.D.,El Bakkouri, M.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Hui, R.,Amain, M.,Lin, Y.H.,Structural Genomics Consortium (SGC) (deposition date: 2015-06-25, release date: 2015-07-22, Last modification date: 2023-09-27)

• Primary citation: Jiang, D.Q.,Tempel, W.,Loppnau, P.,Graslund, S.,Hou, C.F.D.,El Bakkouri, M.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Hui, R.,Amani, M.,Lin, Y.H.; Crystal Structure Analysis of PP-BRD20 from Tb427tmp; to be published,

Experimental method

X-RAY DIFFRACTION (1.95 Å)