5C8G

Crystal Structure Analysis of PP-BRD20 from Tb427tmp complexed with BI-2536

5C8G の概要

• エントリーDOI: 10.2210/pdb5c8g/pdb
• 分子名称: PP-BRD20, 4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxy-N-(1-methylpiperidin-4-yl)benzamide, UNKNOWN ATOM OR ION, ... (4 entities in total)
• 機能のキーワード: structural genomics consortium, sgc, bromodomain, pp-brd20, tb427tmp, gene regulation
• 由来する生物種: Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 32784.95

構造登録者

Jiang, D.Q.,Tempel, W.,Loppnau, P.,Graslund, S.,Hou, C.F.D.,El Bakkouri, M.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Hui, R.,Amain, M.,Lin, Y.H.,Structural Genomics Consortium (SGC) (登録日: 2015-06-25, 公開日: 2015-07-22, 最終更新日: 2023-09-27)

• 主引用文献: Jiang, D.Q.,Tempel, W.,Loppnau, P.,Graslund, S.,Hou, C.F.D.,El Bakkouri, M.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Hui, R.,Amani, M.,Lin, Y.H.; Crystal Structure Analysis of PP-BRD20 from Tb427tmp; to be published,

実験手法

X-RAY DIFFRACTION (1.95 Å)