5C4G

Crystal structure of an engineered construct of phosphatidylinositol 4 kinase III beta with the inhibitor BQR695 in complex with GDP loaded Rab11

5C4G の概要

• エントリーDOI: 10.2210/pdb5c4g/pdb
• 分子名称: Ras-related protein Rab-11A, Phosphatidylinositol 4-kinase beta, MAGNESIUM ION, ... (6 entities in total)
• 機能のキーワード: protein-protein complex, lipid kinase, gtpase complex, transferase-signaling protein complex, transferase/signaling protein
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 86387.68

構造登録者

Burke, J.E.,Fowler, M.L. (登録日: 2015-06-18, 公開日: 2016-01-20, 最終更新日: 2023-09-27)

• 主引用文献: Fowler, M.L.,McPhail, J.A.,Jenkins, M.L.,Masson, G.R.,Rutaganira, F.U.,Shokat, K.M.,Williams, R.L.,Burke, J.E.; Using hydrogen deuterium exchange mass spectrometry to engineer optimized constructs for crystallization of protein complexes: Case study of PI4KIII beta with Rab11.; Protein Sci., 25:826-839, 2016; PubMed: 26756197; DOI: 10.1002/pro.2879

実験手法

X-RAY DIFFRACTION (3.2 Å)