5C15

K428A mutant nuclease domain of the large terminase subunit gp2 of bacterial virus Sf6 with Manganese

Summary for 5C15

Entry DOI	10.2210/pdb5c15/pdb
Related	4IDH 5C10 5C12 5C2D 5C2F
Descriptor	Gene 2 protein, MANGANESE (II) ION (3 entities in total)
Functional Keywords	nuclease domain, metal binding site, metal binding protein
Biological source	Enterobacteria phage Sf6 (Shigella flexneri bacteriophage VI)
Total number of polymer chains	1
Total formula weight	30800.49
Authors	Zhao, H.,Tang, L. (deposition date: 2015-06-12, release date: 2015-10-21, Last modification date: 2023-11-15)
Primary citation	Zhao, H.,Lin, Z.,Lynn, A.Y.,Varnado, B.,Beutler, J.A.,Murelli, R.P.,Le Grice, S.F.,Tang, L. Two distinct modes of metal ion binding in the nuclease active site of a viral DNA-packaging terminase: insight into the two-metal-ion catalytic mechanism. Nucleic Acids Res., 43:11003-11016, 2015 Cited by PubMed: 26450964 DOI: 10.1093/nar/gkv1018 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.57 Å)

Structure validation