5BXJ

Complex of the Fk1 domain mutant A19T of FKBP51 with 4-Nitrophenol

Summary for 5BXJ

DescriptorPeptidyl-prolyl cis-trans isomerase FKBP5, P-NITROPHENOL (3 entities in total)
Functional Keywordscochaperone, fk506, 4-nitrophenol, isomerase
Biological sourceHomo sapiens (Human)
Cellular locationCytoplasm Q13451
Total number of polymer chains1
Total molecular weight14296.38
Authors
Wu, D.,Tao, X.,Chen, Z.,Han, J.,Jia, W.,Li, X.,Wang, Z.,He, Y.X. (deposition date: 2015-06-09, release date: 2016-05-25)
Primary citation
Wu, D.,Tao, X.,Chen, Z.P.,Han, J.T.,Jia, W.J.,Zhu, N.,Li, X.,Wang, Z.,He, Y.X.
The environmental endocrine disruptor p-nitrophenol interacts with FKBP51, a positive regulator of androgen receptor and inhibits androgen receptor signaling in human cells
J. Hazard. Mater., 307:193-201, 2016
PubMed: 26780698 (PDB entries with the same primary citation)
DOI: 10.1016/j.jhazmat.2015.12.045
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.24 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.1981003.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

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