5BTS
Structural and biophysical characterization of a covalent insulin dimer formed during storage of neutral formulation of human insulin
Summary for 5BTS
Entry DOI | 10.2210/pdb5bts/pdb |
Descriptor | Insulin A chain, Insulin B chain (3 entities in total) |
Functional Keywords | insulin, hormone, hmwp |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 5817.65 |
Authors | Norrman, M.,Hjorth, C.F. (deposition date: 2015-06-03, release date: 2016-03-09, Last modification date: 2019-02-20) |
Primary citation | Hjorth, C.F.,Norrman, M.,Wahlund, P.O.,Benie, A.J.,Petersen, B.O.,Jessen, C.M.,Pedersen, T.A.,Vestergaard, K.,Steensgaard, D.B.,Pedersen, J.S.,Naver, H.,Hubalek, F.,Poulsen, C.,Otzen, D. Structure, Aggregation, and Activity of a Covalent Insulin Dimer Formed During Storage of Neutral Formulation of Human Insulin. J.Pharm.Sci., 105:1376-1386, 2016 Cited by PubMed: 26921119DOI: 10.1016/j.xphs.2016.01.003 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.77 Å) |
Structure validation
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