5BT3
Crystal structure of EP300 bromodomain in complex with SGC-CBP30 chemical probe
5BT3 の概要
エントリーDOI | 10.2210/pdb5bt3/pdb |
分子名称 | Histone acetyltransferase p300, 2-[2-(3-chloro-4-methoxyphenyl)ethyl]-5-(3,5-dimethyl-1,2-oxazol-4-yl)-1-[(2S)-2-(morpholin-4-yl)propyl]-1H-benzimidazole, ISOPROPYL ALCOHOL, ... (4 entities in total) |
機能のキーワード | p300, transcription regulation, histone acetyltransferase, structural genomics, structural genomics consortium, sgc, transcription |
由来する生物種 | Homo sapiens (Human) |
細胞内の位置 | Cytoplasm: Q09472 |
タンパク質・核酸の鎖数 | 1 |
化学式量合計 | 14395.93 |
構造登録者 | Tallant, C.,Hay, D.,Krojer, T.,Nunez-Alonso, G.,Picaud, S.,Newman, J.A.,Fedorov, O.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Brennan, P.E.,Knapp, S.,Structural Genomics Consortium (SGC) (登録日: 2015-06-02, 公開日: 2015-07-01, 最終更新日: 2024-01-10) |
主引用文献 | Tallant, C.,Hay, D.,Krojer, T.,Nunez-Alonso, G.,Picaud, S.,Newman, J.A.,Fedorov, O.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Brennan, P.E.,Knapp, S. Crystal structure of EP300 bromodomain in complex with a 3,5-dimethylisoxazol ligand To Be Published, |
実験手法 | X-RAY DIFFRACTION (1.05 Å) |
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