5BQX

Crystal structure of human STING in complex with 3'2'-cGAMP

Summary for 5BQX

Entry DOI	10.2210/pdb5bqx/pdb
Related	4KSY
Descriptor	Stimulator of interferon genes protein, 3'2'-cGAMP (3 entities in total)
Functional Keywords	sting, 3'2'-cgamp, immune system
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	27855.06
Authors	Wu, J.,Zhang, X.,Chen, Z.J.,Chen, C. (deposition date: 2015-05-29, release date: 2015-06-24, Last modification date: 2024-03-06)
Primary citation	Shi, H.,Wu, J.,Chen, Z.J.,Chen, C. Molecular basis for the specific recognition of the metazoan cyclic GMP-AMP by the innate immune adaptor protein STING. Proc.Natl.Acad.Sci.USA, 112:8947-8952, 2015 Cited by PubMed: 26150511 DOI: 10.1073/pnas.1507317112 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation