5BQN

Crystal structure of the LHn fragment of botulinum neurotoxin type D, mutant H233Y E230Q

5BQN の概要

• エントリーDOI: 10.2210/pdb5bqn/pdb
• 分子名称: Botulinum neurotoxin type D,Botulinum neurotoxin type D, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID (3 entities in total)
• 機能のキーワード: botulinum neurotoxin, targeted secretion inhibitors, endopeptidase, type d, protein engineering, hydrolase
• 由来する生物種: Clostridium botulinum; 詳細
• 細胞内の位置: Botulinum neurotoxin D light chain: Secreted. Botulinum neurotoxin D heavy chain: Secreted: P19321
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 102093.90

構造登録者

Masuyer, G.,Davies, J.R.,Moore, K.,Chaddock, J.A.,Acharya, K.R. (登録日: 2015-05-29, 公開日: 2015-08-19, 最終更新日: 2024-01-10)

• 主引用文献: Masuyer, G.,Davies, J.R.,Moore, K.,Chaddock, J.A.,Ravi Acharya, K.; Structural analysis of Clostridium botulinum neurotoxin type D as a platform for the development of targeted secretion inhibitors.; Sci Rep, 5:13397-13397, 2015; PubMed: 26324071; DOI: 10.1038/srep13397

実験手法

X-RAY DIFFRACTION (2.3 Å)