5BP4

Modifying region (DH-ER-KR) of a mycocerosic acid synthase-like (MAS-like) PKS

This is a non-PDB format compatible entry.

Summary for 5BP4

• Entry DOI: 10.2210/pdb5bp4/pdb
• Related: 5bp2 5bp3 5bp5
• Descriptor: Mycocerosic acid synthase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (2 entities in total)
• Functional Keywords: transferase, polyketide, dehydratase, ketoreductase, enoylreductase
• Biological source: Mycobacterium smegmatis
• Cellular location: Cell membrane ; Lipid-anchor : A0R1E8
• Total number of polymer chains: 18
• Total formula weight: 2199539.96

Authors

Herbst, D.A.,Jakob, P.R.,Zaehringer, F.,Maier, T. (deposition date: 2015-05-27, release date: 2016-03-09, Last modification date: 2024-01-10)

• Primary citation: Herbst, D.A.,Jakob, R.P.,Zahringer, F.,Maier, T.; Mycocerosic acid synthase exemplifies the architecture of reducing polyketide synthases.; Nature, 531:533-537, 2016; PubMed: 26976449; DOI: 10.1038/nature16993

Experimental method

X-RAY DIFFRACTION (3.75 Å)