5BOD

Crystal structure of Streptococcus pneumonia ParE inhibitor

Summary for 5BOD

• Entry DOI: 10.2210/pdb5bod/pdb
• Related: 5BOC
• Descriptor: DNA topoisomerase 4 subunit B, (2R)-N-[3-(3,5-dimethylphenyl)-1H-pyrazol-5-yl]-1,4-dioxane-2-carboxamide (3 entities in total)
• Functional Keywords: inhibitor, topoisomerase, pare, isomerase-isomerase inhibitor complex, isomerase/isomerase inhibitor
• Biological source: Streptococcus pneumoniae R6
• Total number of polymer chains: 1
• Total formula weight: 24902.06

Authors

Tan, Y.W.,Chen, G.,Hung, A.W.,Hill, J. (deposition date: 2015-05-27, release date: 2015-06-17, Last modification date: 2023-11-08)

• Primary citation: Chen, G.Y.,Ng, F.M.,Tan, Y.W.,Poulsen, A.,Seetoh, W.,Lin, G.,Kang, C.,Then, S.W.,Ahmad, N.H.,Wong, Y.L.,Ng, H.Q.,Chia, B.C.S.,Lau, Q.Y.,Hill, J.,Hung, A.W.,Keller, T.H.; Application of Fragment-based Drug Discovery against DNA GyraseB; to be published,

Experimental method

X-RAY DIFFRACTION (2.2 Å)