5BO4
Structure of SOCS2:Elongin C:Elongin B from DMSO-treated crystals
Summary for 5BO4
Entry DOI | 10.2210/pdb5bo4/pdb |
Descriptor | Suppressor of cytokine signaling 2, Transcription elongation factor B polypeptide 2, Transcription elongation factor B polypeptide 1, ... (4 entities in total) |
Functional Keywords | signaling protein, ubiquitin ligase, suppressor of cytokine signalling |
Biological source | Homo sapiens (Human) More |
Cellular location | Nucleus : Q15370 Q15369 |
Total number of polymer chains | 18 |
Total formula weight | 253225.53 |
Authors | Gadd, M.S.,Bulatov, E.,Ciulli, A. (deposition date: 2015-05-27, release date: 2015-07-08, Last modification date: 2024-10-09) |
Primary citation | Gadd, M.S.,Bulatov, E.,Ciulli, A. Serendipitous SAD Solution for DMSO-Soaked SOCS2-ElonginC-ElonginB Crystals Using Covalently Incorporated Dimethylarsenic: Insights into Substrate Receptor Conformational Flexibility in Cullin RING Ligases. Plos One, 10:e0131218-e0131218, 2015 Cited by PubMed: 26121586DOI: 10.1371/journal.pone.0131218 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
Download full validation report