5B6F

Crystal structure of the Fab fragment of an anti-Leukotriene C4 monoclonal antibody complexed with LTC4

Summary for 5B6F

• Entry DOI: 10.2210/pdb5b6f/pdb
• Descriptor: anti-leukotriene C4 monoclonal antibody immunoglobulin kappa light chain, anti-leukotriene C4 monoclonal antibody immunoglobulin gamma1 heavy chain, (5~{S},6~{R},7~{E},9~{E},11~{Z},14~{Z})-6-[(2~{R})-2-[[(4~{S})-4-azanyl-5-oxidanyl-5-oxidanylidene-pentanoyl]amino]-3-(2-hydroxy-2-oxoethylamino)-3-oxidanylidene-propyl]sulfanyl-5-oxidanyl-icosa-7,9,11,14-tetraenoic acid, ... (6 entities in total)
• Functional Keywords: immunogloblin, anti-leukotriene c4 antibody, leukotriene c4, fab fragment, immune system
• Biological source: Mus musculus; More
• Total number of polymer chains: 8
• Total formula weight: 212520.11

Authors

Sugahara, M.,Ago, H.,Saino, H.,Miyano, M. (deposition date: 2016-05-27, release date: 2017-05-31, Last modification date: 2019-07-24)

• Primary citation: Sugahara, M.,Ago, H.,Saino, H.,Miyano, M.,Yamamoto, S.,Takahashi, Y.; Crystal structure of the Fab fragment of an anti-Leukotriene C4 monoclonal antibody complexed with LTC4; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.1 Å)