5B4V

Crystal structure of D-3-hydroxybutyrate dehydrogenase from Alcaligenes faecalis complexed with NAD+ and an inhibitor methylmalonate

5B4V の概要

• エントリーDOI: 10.2210/pdb5b4v/pdb
• 関連するPDBエントリー: 5B4T 5B4U
• 分子名称: 3-hydroxybutyrate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, METHYLMALONIC ACID, ... (6 entities in total)
• 機能のキーワード: short-chain dehydrogenases/reductases, inhibitor, complex, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
• 由来する生物種: Alcaligenes faecalis
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 28004.88

構造登録者

Kanazawa, H.,Tsunoda, M.,Hoque, M.M.,Suzuki, K.,Yamamoto, T.,Takenaka, A. (登録日: 2016-04-19, 公開日: 2016-08-17, 最終更新日: 2024-03-20)

• 主引用文献: Kanazawa, H.,Hoque, M.M.,Tsunoda, M.,Suzuki, K.,Yamamoto, T.,Kawai, G.,Kondo, J.,Takenaka, A.; Structural insights into the catalytic reaction trigger and inhibition of D-3-hydroxybutyrate dehydrogenase; Acta Crystallogr.,Sect.F, 72:507-515, 2016; PubMed: 27380367; DOI: 10.1107/S2053230X16007767

実験手法

X-RAY DIFFRACTION (1.5 Å)