5AZZ

Crystal structure of seleno-insulin

Summary for 5AZZ

DescriptorInsulin A chain, Insulin B chain (3 entities in total)
Functional Keywordsselenocysteine, insulin, hormone
Biological sourceBos taurus (Bovine)
Cellular locationSecreted P01317 P01317
Total number of polymer chains2
Total molecular weight6099.75
Authors
Watanabe, S.,Okumura, M.,Arai, K.,Takei, T.,Asahina, Y.,Hojo, H.,Iwaoka, M.,Inaba, K. (deposition date: 2015-10-23, release date: 2017-05-03, Last modification date: 2017-06-14)
Primary citation
Arai, K.,Takei, T.,Okumura, M.,Watanabe, S.,Amagai, Y.,Asahina, Y.,Moroder, L.,Hojo, H.,Inaba, K.,Iwaoka, M.
Preparation of Selenoinsulin as a Long-Lasting Insulin Analogue.
Angew. Chem. Int. Ed. Engl., 56:5522-5526, 2017
PubMed: 28394477 (PDB entries with the same primary citation)
DOI: 10.1002/anie.201701654
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.45 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.204902.4%4.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution