5AXE

Crystal Structure Analysis of DNA Duplexes containing sulfoamide-bridged nucleic acid (SuNA-NH)

Summary for 5AXE

• Entry DOI: 10.2210/pdb5axe/pdb
• Related: 5AXF
• Descriptor: DNA (5'-D(*GP*CP*GP*TP*AP*(LSH)P*AP*CP*GP*C)-3') (2 entities in total)
• Functional Keywords: a-form dna, sulfonamide-bridged nucleic acid, suna[nh], antisense, dna
• Biological source: synthetic construct
• Total number of polymer chains: 2
• Total formula weight: 6272.19

Authors

Mitsuoka, Y.,Aoyama, H.,Kugimiya, A.,Fujimura, Y.,Yamamoto, T.,Waki, R.,Wada, F.,Tahara, S.,Sawamura, M.,Noda, M.,Hari, Y.,Obika, S. (deposition date: 2015-07-28, release date: 2016-07-20, Last modification date: 2023-11-08)

• Primary citation: Mitsuoka, Y.,Aoyama, H.,Kugimiya, A.,Fujimura, Y.,Yamamoto, T.,Waki, R.,Wada, F.,Tahara, S.,Sawamura, M.,Noda, M.,Hari, Y.,Obika, S.; Effect of an N-substituent in sulfonamide-bridged nucleic acid (SuNA) on hybridization ability and duplex structure.; Org.Biomol.Chem., 14:6531-6538, 2016; PubMed: 27296230; DOI: 10.1039/c6ob01051b

Experimental method

X-RAY DIFFRACTION (0.95 Å)