5AMA

Crystal structure of the Angiotensin-1 converting enzyme N-domain in complex with amyloid-beta 1-16

Summary for 5AMA

• Entry DOI: 10.2210/pdb5ama/pdb
• Related: 5AM8 5AM9 5AMB 5AMC
• Descriptor: ANGIOTENSIN-CONVERTING ENZYME, CHLORIDE ION, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (14 entities in total)
• Functional Keywords: metalloprotease, amyloid- beta, hydrolase
• Biological source: HOMO SAPIENS (HUMAN)
• Total number of polymer chains: 4
• Total formula weight: 299937.54

Authors

Masuyer, G.,Larmuth, K.M.,Douglas, R.G.,Sturrock, E.D.,Acharya, K.R. (deposition date: 2015-03-10, release date: 2016-01-13, Last modification date: 2024-01-10)

• Primary citation: Larmuth, K.M.,Masuyer, G.,Douglas, R.G.,Sturrock, E.D.,Acharya, K.R.; The Kinetic and Structural Characterisation of Amyloid-Beta Metabolism by Human Angiotensin-1- Converting Enzyme (Ace); FEBS J., 283:1060-, 2016; PubMed: 26748546; DOI: 10.1111/FEBS.13647

Experimental method

X-RAY DIFFRACTION (1.8 Å)