5AL8
Transthyretin binding heterogeneity and anti-amyloidogenic activity of natural polyphenols and their metabolites: daidzein-7-O- glucuronide
Summary for 5AL8
Entry DOI | 10.2210/pdb5al8/pdb |
Related | 5AKS 5AKT 5AKV 5AL0 |
Descriptor | TRANSTHYRETIN, DAIDZEIN-7-O-GLUCURONIDE (3 entities in total) |
Functional Keywords | transport protein, amyloid, fibrillogenesis, fibrillogenesis inhibitors, polyphenols, polyphenol metabolites, negative cooperativity |
Biological source | Homo sapiens (HUMAN) |
Total number of polymer chains | 2 |
Total formula weight | 28415.44 |
Authors | Florio, P.,Foll, C.,Cianci, M.,Del Rio, D.,Zanotti, G.,Berni, R. (deposition date: 2015-03-06, release date: 2015-10-21, Last modification date: 2024-01-10) |
Primary citation | Florio, P.,Folli, C.,Cianci, M.,Del Rio, D.,Zanotti, G.,Berni, R. Transthyretin Binding Heterogeneity and Anti-Amyloidogenic Activity of Natural Polyphenols and Their Metabolites J.Biol.Chem., 290:29769-, 2015 Cited by PubMed: 26468275DOI: 10.1074/JBC.M115.690172 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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