5AKT

Transthyretin binding heterogeneity and anti-amyloidogenic activity of natural polyphenols and their metabolites: resveratrol-4'-O- glucuronide

5AKT の概要

• エントリーDOI: 10.2210/pdb5akt/pdb
• 関連するPDBエントリー: 5AKS 5AKV 5AL0 5AL8
• 分子名称: TRANSTHYRETIN, SULFATE ION, Resveratrol-4'-O-glucuronide, ... (4 entities in total)
• 機能のキーワード: transport protein, amyloid, fibrillogenesis, fibrillogenesis inhibitors, polyphenols, polyphenol metabolites, negative cooperativity
• 由来する生物種: Homo sapiens (HUMAN)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 28555.58

構造登録者

Florio, P.,Folli, C.,Cianci, M.,Del Rio, D.,Zanotti, G.,Berni, R. (登録日: 2015-03-05, 公開日: 2015-10-21, 最終更新日: 2024-01-10)

• 主引用文献: Florio, P.,Folli, C.,Cianci, M.,Del Rio, D.,Zanotti, G.,Berni, R.; Transthyretin Binding Heterogeneity and Anti-Amyloidogenic Activity of Natural Polyphenols and Their Metabolites; J.Biol.Chem., 290:29769-, 2015; PubMed: 26468275; DOI: 10.1074/JBC.M115.690172

実験手法

X-RAY DIFFRACTION (1.35 Å)