5AJQ

Human LOK (STK10) in complex with Bosutinib

Summary for 5AJQ

• Entry DOI: 10.2210/pdb5ajq/pdb
• Descriptor: SERINE/THREONINE-PROTEIN KINASE 10, 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile, CHLORIDE ION, ... (5 entities in total)
• Functional Keywords: transferase
• Biological source: HOMO SAPIENS (HUMAN)
• Cellular location: Cell membrane ; Peripheral membrane protein : O94804
• Total number of polymer chains: 2
• Total formula weight: 68031.62

Authors

Elkins, J.M.,Salah, E.,Pinkas, D.M.,Krojer, T.,Kopec, J.,Bountra, C.,Edwards, A.M.,Knapp, S. (deposition date: 2015-02-26, release date: 2015-03-11, Last modification date: 2015-04-08)

• Primary citation: Elkins, J.M.,Salah, E.,Knapp, S.; Stk10 with Bosutinib; To be Published,

Experimental method

X-RAY DIFFRACTION (2.2 Å)