5AHG

Thrombin in complex with ((4-chlorophenyl)sulfamoyl))diemethylamine

5AHG の概要

• エントリーDOI: 10.2210/pdb5ahg/pdb
• 分子名称: THROMBIN HEAVY CHAIN, HIRUDIN VARIANT-2, THROMBIN LIGHT CHAIN, ... (10 entities in total)
• 機能のキーワード: hydrolase, hydrolase inhibitor complex, serine protease, blood coagulation, blood clotting, convertion of fibrinogen to fibrin, blood clotting inhibitor, thrombin inhibitor, fragment, glycosylation, blood
• 由来する生物種: HOMO SAPIENS (HUMAN); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 35477.74

構造登録者

Ruehmann, E.,Heine, A.,Klebe, G. (登録日: 2015-02-06, 公開日: 2015-08-26, 最終更新日: 2024-01-10)

• 主引用文献: Ruehmann, E.,Betz, M.,Heine, A.,Klebe, G.; Fragments Can Bind Either More Enthalpy or Entropy-Driven: Crystal Structures and Residual Hydration Pattern Suggest Why.; J.Med.Chem., 58:6960-, 2015; PubMed: 26270568; DOI: 10.1021/ACS.JMEDCHEM.5B00812

実験手法

X-RAY DIFFRACTION (1.24 Å)