5AFY
Thrombin in complex with 3-chloro-benzamide
Summary for 5AFY
Entry DOI | 10.2210/pdb5afy/pdb |
Related | 5AF9 5AFZ |
Descriptor | Prothrombin, Hirudin-2, SODIUM ION, ... (10 entities in total) |
Functional Keywords | hydrolase, hydrolase inhibitor complex, serine protease, blood coagulation, blood clotting, convertion of fibrinogen to fibrin, blood clotting inhibitor, thrombin inhibitor, fragment, glycosylation, blood |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 35490.71 |
Authors | Ruehmann, E.,Heine, A.,Klebe, G. (deposition date: 2015-01-27, release date: 2015-08-26, Last modification date: 2024-10-16) |
Primary citation | Ruehmann, E.,Betz, M.,Heine, A.,Klebe, G. Fragments Can Bind Either More Enthalpy or Entropy-Driven: Crystal Structures and Residual Hydration Pattern Suggest Why. J.Med.Chem., 58:6960-, 2015 Cited by PubMed: 26270568DOI: 10.1021/ACS.JMEDCHEM.5B00812 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.12 Å) |
Structure validation
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