5AEG

A bacterial protein structure in glycoside hydrolase family 31.

5AEG の概要

• エントリーDOI: 10.2210/pdb5aeg/pdb
• 関連するPDBエントリー: 5AED 5AEE
• 分子名称: ALPHA-GLUCOSIDASE YIHQ, CALCIUM ION, CHLORIDE ION, ... (6 entities in total)
• 機能のキーワード: hydrolase, gh31, alpha-sulfoquinovosidase
• 由来する生物種: ESCHERICHIA COLI
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 157591.60

構造登録者

Jin, Y.,Speciale, G.,Davies, G.J.,Williams, S.J.,Goddard-Borger, E.D. (登録日: 2015-08-30, 公開日: 2016-02-10, 最終更新日: 2024-11-13)

主引用文献

Speciale, G.,Jin, Y.,Davies, G.J.,Williams, S.J.,Goddard-Borger, E.D.
Yihq is a Sulfoquinovosidase that Cleaves Sulfoquinovosyl Diacylglyceride Sulfolipids.
Nat.Chem.Biol., 12:215-, 2016

PubMed Abstract: Sulfoquinovose is produced by photosynthetic organisms at a rate of 10(10) tons per annum and is degraded by bacteria as a source of carbon and sulfur. We have identified Escherichia coli YihQ as the first dedicated sulfoquinovosidase and the gateway enzyme to sulfoglycolytic pathways. Structural and mutagenesis studies unveiled the sequence signatures for binding the distinguishing sulfonate residue and revealed that sulfoquinovoside degradation is widespread across the tree of life.

PubMed: 26878550
DOI: 10.1038/NCHEMBIO.2023

実験手法

X-RAY DIFFRACTION (1.85 Å)