5ACL

Mcg immunoglobulin variable domain with sulfasalazine

Summary for 5ACL

• Entry DOI: 10.2210/pdb5acl/pdb
• Related: 5ACM
• Descriptor: MCG, 2-HYDROXY-(5-([4-(2-PYRIDINYLAMINO)SULFONYL]PHENYL)AZO)BENZOIC ACID, SULFATE ION, ... (4 entities in total)
• Functional Keywords: immune system, mcg, immunoglobulin variable domain, methylene blue
• Biological source: HOMO SAPIENS (HUMAN)
• Cellular location: Secreted : P01709
• Total number of polymer chains: 1
• Total formula weight: 12059.97

Authors

Brumshtein, B.,Esswein, S.R.,Salwinski, L.,Phillips, M.L.,Ly, A.T.,Cascio, D.,Sawaya, M.R.,Eisenberg, D.S. (deposition date: 2015-08-17, release date: 2015-12-02, Last modification date: 2024-01-10)

• Primary citation: Brumshtein, B.,Esswein, S.R.,Salwinski, L.,Phillips, M.L.,Ly, A.T.,Cascio, D.,Sawaya, M.R.,Eisenberg, D.S.; Inhibition by small-molecule ligands of formation of amyloid fibrils of an immunoglobulin light chain variable domain.; Elife, 4:e10935-e10935, 2015; PubMed: 26576950; DOI: 10.7554/eLife.10935

Experimental method

X-RAY DIFFRACTION (1.49 Å)