5AC4

GH20C, Beta-hexosaminidase from Streptococcus pneumoniae in complex with GalNAc

Summary for 5AC4

• Entry DOI: 10.2210/pdb5ac4/pdb
• Related: 5AC5
• Descriptor: N-ACETYL-BETA-D-GLUCOSAMINIDASE, 2-acetamido-2-deoxy-beta-D-galactopyranose (3 entities in total)
• Functional Keywords: hydrolase, bacterial proteins, carbohydrate conformation, catalytic domain, host-pathogen interactions, hydrolysis, polysaccharides, virulence factors
• Biological source: STREPTOCOCCUS PNEUMONIAE
• Total number of polymer chains: 2
• Total formula weight: 148803.48

Authors

Cid, M.,Robb, C.S.,Higgins, M.A.,Boraston, A.B. (deposition date: 2015-08-11, release date: 2015-09-23, Last modification date: 2024-01-10)

• Primary citation: Robb, M.,Robb, C.S.,Higgins, M.A.,Hobbs, J.K.,Paton, J.C.,Boraston, A.B.; A Second beta-Hexosaminidase Encoded in the Streptococcus pneumoniae Genome Provides an Expanded Biochemical Ability to Degrade Host Glycans.; J. Biol. Chem., 290:30888-30900, 2015; PubMed: 26491009; DOI: 10.1074/jbc.M115.688630

Experimental method

X-RAY DIFFRACTION (2.08 Å)