5AAO

Crystal structure of fluorogen-activating designed ankyrin repeat protein (DARPin) dimer in complex with malachite green

5AAO の概要

• エントリーDOI: 10.2210/pdb5aao/pdb
• 分子名称: FAD3210, 4-[[4-(dimethylamino)cyclohexa-2,5-dien-1-ylidene]-(4-methoxyphenyl)methyl]-N,N-dimethyl-aniline (3 entities in total)
• 機能のキーワード: fluorescent protein, homodimer, designed ankyrin repeat protein (darpin), fluorogen-activation, malachite green
• 由来する生物種: SYNTHETIC CONSTRUCT
• タンパク質・核酸の鎖数: 12
• 化学式量合計: 224784.14

構造登録者

Batyuk, A.,Schuetz, M.,Kummer, L.,Wu, Y.,Mittl, P.,Plueckthun, A. (登録日: 2015-07-27, 公開日: 2016-02-03, 最終更新日: 2024-01-10)

• 主引用文献: Schutz, M.,Batyuk, A.,Klenk, C.,Kummer, L.,de Picciotto, S.,Gulbakan, B.,Wu, Y.,Newby, G.A.,Zosel, F.,Schoppe, J.,Sedlak, E.,Mittl, P.R.,Zenobi, R.,Wittrup, K.D.,Pluckthun, A.; Generation of Fluorogen-Activating Designed Ankyrin Repeat Proteins (FADAs) as Versatile Sensor Tools.; J. Mol. Biol., 428:1272-1289, 2016; PubMed: 26812208; DOI: 10.1016/j.jmb.2016.01.017

実験手法

X-RAY DIFFRACTION (2.6 Å)