5A6K

GH20C, Beta-hexosaminidase from Streptococcus pneumoniae in complex with Gal-NGT

5A6K の概要

• エントリーDOI: 10.2210/pdb5a6k/pdb
• 関連するPDBエントリー: 5A69 5A6A 5A6B 5A6J
• 分子名称: GH20C, (2S,3aR,5R,6R,7R,7aR)-5-(hydroxymethyl)-2-methyl-2,3a,5,6,7,7a-hexahydro-1H-pyrano[3,2-d][1,3]thiazole-6,7-diol (3 entities in total)
• 機能のキーワード: beta-hexosaminidase, streptococcus pneumoniae, bacterial proteins, carbohydrate conformation, catalytic domain, enzyme inhibitors, host-pathogen interactions, hydrogen bonding, hydrolysis, models, polysaccharides, protein binding, virulence factors, hydrolase
• 由来する生物種: STREPTOCOCCUS PNEUMONIAE
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 148805.58

構造登録者

Cid, M.,Robb, C.S.,Higgins, M.A.,Boraston, A.B. (登録日: 2015-06-26, 公開日: 2015-09-23, 最終更新日: 2024-01-10)

• 主引用文献: Robb, M.,Robb, C.S.,Higgins, M.A.,Hobbs, J.K.,Paton, J.C.,Boraston, A.B.; A Second Beta-Hexosaminidase Encoded in the Streptococcus Pneumoniae Genome Provides an Expanded Biochemical Ability to Degrade Host Glycans; J.Biol.Chem., 290:30888-, 2015; PubMed: 26491009; DOI: 10.1074/JBC.M115.688630

実験手法

X-RAY DIFFRACTION (2.1 Å)