5A6B

GH20C, Beta-hexosaminidase from Streptococcus pneumoniae in complex with PUGNAc

5A6B の概要

• エントリーDOI: 10.2210/pdb5a6b/pdb
• 関連するPDBエントリー: 5A69 5A6A 5A6J 5A6K
• 分子名称: N-ACETYL-BETA-D-GLUCOSAMINIDASE, O-(2-ACETAMIDO-2-DEOXY D-GLUCOPYRANOSYLIDENE) AMINO-N-PHENYLCARBAMATE, MAGNESIUM ION, ... (5 entities in total)
• 機能のキーワード: hydrolase, beta-hexosaminidase, streptococcus pneumoniae, bacterial proteins, carbohydrate conformation, catalytic domain, enzyme inhibitors, host-pathogen interactions, hydrogen bonding, hydrolysis, models, polysaccharides, protein binding, virulence factors
• 由来する生物種: STREPTOCOCCUS PNEUMONIAE; 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 297894.87

構造登録者

Cid, M.,Robb, C.S.,Higgins, M.A.,Boraston, A.B. (登録日: 2015-06-24, 公開日: 2015-09-23, 最終更新日: 2024-01-10)

• 主引用文献: Robb, M.,Robb, C.S.,Higgins, M.A.,Hobbs, J.K.,Paton, J.C.,Boraston, A.B.; A Second beta-Hexosaminidase Encoded in the Streptococcus pneumoniae Genome Provides an Expanded Biochemical Ability to Degrade Host Glycans.; J. Biol. Chem., 290:30888-30900, 2015; PubMed: 26491009; DOI: 10.1074/jbc.M115.688630

実験手法

X-RAY DIFFRACTION (1.77 Å)