5A69

GH20C, Beta-hexosaminidase from Streptococcus pneumoniae in complex with Gal-PUGNAc

5A69 の概要

• エントリーDOI: 10.2210/pdb5a69/pdb
• 関連するPDBエントリー: 5A6A 5A6B 5A6J 5A6K
• 分子名称: N-ACETYL-BETA-D-GLUCOSAMINIDASE, [(Z)-[(3R,4R,5R,6R)-3-acetamido-6-(hydroxymethyl)-4,5-bis(oxidanyl)oxan-2-ylidene]amino] N-phenylcarbamate (3 entities in total)
• 機能のキーワード: hydrolase, beta-hexosaminidase, carbohydrate conformation, catalytic domain, enzyme inhibitors, host-pathogen interactions, hydrogen bonding, hydrolysis, polysaccharides, protein binding, virulence factors
• 由来する生物種: STREPTOCOCCUS PNEUMONIAE
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 74534.84

構造登録者

Cid, M.,Robb, C.S.,Higgins, M.A.,Boraston, A.B. (登録日: 2015-06-24, 公開日: 2015-09-23, 最終更新日: 2024-01-10)

• 主引用文献: Robb, M.,Robb, C.S.,Higgins, M.A.,Hobbs, J.K.,Paton, J.C.,Boraston, A.B.; A Second beta-Hexosaminidase Encoded in the Streptococcus pneumoniae Genome Provides an Expanded Biochemical Ability to Degrade Host Glycans.; J. Biol. Chem., 290:30888-30900, 2015; PubMed: 26491009; DOI: 10.1074/jbc.M115.688630

実験手法

X-RAY DIFFRACTION (2.2 Å)