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5ZSL

Crystal structure of monkey TLR7 in complex with GGUUGG

Summary for 5ZSL
Entry DOI10.2210/pdb5zsl/pdb
DescriptorToll-like receptor 7, RNA (5'-R(P*UP*UP*GP*A)-3'), 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
Functional Keywordsinnate immunity toll-like receptors, immune system
Biological sourceMacaca mulatta (Rhesus macaque)
More
Total number of polymer chains4
Total formula weight198849.33
Authors
Zhang, Z.,Ohto, U.,Shimizu, T. (deposition date: 2018-04-28, release date: 2019-01-30, Last modification date: 2024-03-13)
Primary citationZhang, Z.,Ohto, U.,Shibata, T.,Taoka, M.,Yamauchi, Y.,Sato, R.,Shukla, N.M.,David, S.A.,Isobe, T.,Miyake, K.,Shimizu, T.
Structural Analyses of Toll-like Receptor 7 Reveal Detailed RNA Sequence Specificity and Recognition Mechanism of Agonistic Ligands.
Cell Rep, 25:3371-3381.e5, 2018
Cited by
PubMed: 30566863
DOI: 10.1016/j.celrep.2018.11.081
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.3 Å)
Structure validation

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