5Z8A
Crystal structure of GenB1 from Micromonospora echinospora in complex with JI-20A and PLP (external aldimine)
Summary for 5Z8A
Entry DOI | 10.2210/pdb5z8a/pdb |
Descriptor | C-6' aminotransferase, PYRIDOXAL-5'-PHOSPHATE, (2~{R},3~{R},4~{R},5~{R})-2-[(1~{S},2~{S},3~{R},4~{S},6~{R})-3-[(2~{R},3~{R},4~{R},5~{S},6~{R})-6-(aminomethyl)-3-azany l-4,5-bis(oxidanyl)oxan-2-yl]oxy-4,6-bis(azanyl)-2-oxidanyl-cyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol, ... (4 entities in total) |
Functional Keywords | aminotransferase, plp-binding, transferase |
Biological source | Micromonospora echinospora (Micromonospora purpurea) |
Total number of polymer chains | 2 |
Total formula weight | 95806.18 |
Authors | Hong, S.K.,Cha, S.S. (deposition date: 2018-01-31, release date: 2019-01-16, Last modification date: 2024-03-27) |
Primary citation | Ban, Y.H.,Song, M.C.,Hwang, J.Y.,Shin, H.L.,Kim, H.J.,Hong, S.K.,Lee, N.J.,Park, J.W.,Cha, S.S.,Liu, H.W.,Yoon, Y.J. Complete reconstitution of the diverse pathways of gentamicin B biosynthesis. Nat. Chem. Biol., 15:295-303, 2019 Cited by PubMed: 30643280DOI: 10.1038/s41589-018-0203-4 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.398 Å) |
Structure validation
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