5XZC
Cryo-EM structure of p300-p53 protein complex
Summary for 5XZC
| Entry DOI | 10.2210/pdb5xzc/pdb |
| EMDB information | 6791 |
| Descriptor | Histone acetyltransferase p300, Cellular tumor antigen p53 (2 entities in total) |
| Functional Keywords | transcription factor, autoacetylation, allosteric interaction, catalytically active form, transcription |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 5 |
| Total formula weight | 191695.69 |
| Authors | Ghosh, R.,Roy, S.,Sengupta, J. (deposition date: 2017-07-12, release date: 2019-01-23, Last modification date: 2024-03-27) |
| Primary citation | Ghosh, R.,Kaypee, S.,Shasmal, M.,Kundu, T.K.,Roy, S.,Sengupta, J. Tumor suppressor p53-mediated structural reorganization of the transcriptional coactivator p300. Biochemistry, 2019 Cited by PubMed: 31314496DOI: 10.1021/acs.biochem.9b00333 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (10.7 Å) |
Structure validation
Download full validation report
