5XXY

Crystal structure of PD-L1 complexed with atezolizumab fab at 2.9A

Summary for 5XXY

• Entry DOI: 10.2210/pdb5xxy/pdb
• Descriptor: heavy chain of atezolizumab fab, light chain of atezolizumab fab, Programmed cell death 1 ligand 1, ... (4 entities in total)
• Functional Keywords: pd-l1, atezolizumab, immune system
• Biological source: Homo sapiens; More
• Cellular location: Isoform 1: Cell membrane ; Single-pass type I membrane protein . Isoform 2: Endomembrane system ; Single-pass type I membrane protein : Q9NZQ7
• Total number of polymer chains: 3
• Total formula weight: 63268.73

Authors

Zhou, A.,Zhang, F. (deposition date: 2017-07-05, release date: 2017-09-20, Last modification date: 2023-11-22)

• Primary citation: Zhang, F.,Qi, X.,Wang, X.,Wei, D.,Wu, J.,Feng, L.,Cai, H.,Wang, Y.,Zeng, N.,Xu, T.,Zhou, A.,Zheng, Y.; Structural basis of the therapeutic anti-PD-L1 antibody atezolizumab.; Oncotarget, 8:90215-90224, 2017; PubMed: 29163822; DOI: 10.18632/oncotarget.21652

Experimental method

X-RAY DIFFRACTION (2.9 Å)