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5XAI

dTMP bound Crystal structure of thymidylate kinase (aq_969) from Aquifex Aeolicus VF5

Summary for 5XAI
Entry DOI10.2210/pdb5xai/pdb
Related5XB2 5XB3 5XB5 5XBH
DescriptorThymidylate kinase, PHOSPHATE ION, THYMIDINE-5'-PHOSPHATE, ... (4 entities in total)
Functional Keywordskinase, tranferase, complex, nucleotide binding, transferase
Biological sourceAquifex aeolicus (strain VF5)
Total number of polymer chains2
Total formula weight45640.28
Authors
Biswas, A.,Jeyakanthan, J.,Sekar, K. (deposition date: 2017-03-13, release date: 2017-06-28, Last modification date: 2023-11-22)
Primary citationBiswas, A.,Shukla, A.,Chaudhary, S.K.,Santhosh, R.,Jeyakanthan, J.,Sekar, K.
Structural studies of a hyperthermophilic thymidylate kinase enzyme reveal conformational substates along the reaction coordinate
FEBS J., 284:2527-2544, 2017
Cited by
PubMed: 28627020
DOI: 10.1111/febs.14140
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2 Å)
Structure validation

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