5X8L

PD-L1 in complex with atezolizumab

Summary for 5X8L

• Entry DOI: 10.2210/pdb5x8l/pdb
• Related: 5X8M
• Descriptor: Programmed cell death 1 ligand 1, atezolizumab light chain, atezolizumab heavy chain (3 entities in total)
• Functional Keywords: complex, antibody, immune system
• Biological source: Homo sapiens (Human); More
• Cellular location: Isoform 1: Cell membrane ; Single-pass type I membrane protein . Isoform 2: Endomembrane system ; Single-pass type I membrane protein : Q9NZQ7
• Total number of polymer chains: 15
• Total formula weight: 311223.18

Authors

Heo, Y.S.,Lee, H.T. (deposition date: 2017-03-03, release date: 2017-08-16)

• Primary citation: Lee, H.T.,Lee, J.Y.,Lim, H.,Lee, S.H.,Moon, Y.J.,Pyo, H.J.,Ryu, S.E.,Shin, W.,Heo, Y.S.; Molecular mechanism of PD-1/PD-L1 blockade via anti-PD-L1 antibodies atezolizumab and durvalumab; Sci Rep, 7:5532-5532, 2017; PubMed: 28717238; DOI: 10.1038/s41598-017-06002-8

Experimental method

X-RAY DIFFRACTION (3.1 Å)