5VLI

Computationally designed inhibitor peptide HB1.6928.2.3 in complex with influenza hemagglutinin (A/PuertoRico/8/1934)

Summary for 5VLI

• Entry DOI: 10.2210/pdb5vli/pdb
• Descriptor: Hemagglutinin, Computationally designed peptide HB1.6928.2.3, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
• Functional Keywords: inhibitor, protein design, influenza, hemagglutinin, viral protein-de novo protein complex, viral protein/de novo protein
• Biological source: Influenza A virus (strain A/Puerto Rico/8/1934 H1N1); More
• Total number of polymer chains: 3
• Total formula weight: 63147.79

Authors

Bernard, S.M.,Wilson, I.A. (deposition date: 2017-04-25, release date: 2017-09-27, Last modification date: 2023-10-04)

• Primary citation: Chevalier, A.,Silva, D.A.,Rocklin, G.J.,Hicks, D.R.,Vergara, R.,Murapa, P.,Bernard, S.M.,Zhang, L.,Lam, K.H.,Yao, G.,Bahl, C.D.,Miyashita, S.I.,Goreshnik, I.,Fuller, J.T.,Koday, M.T.,Jenkins, C.M.,Colvin, T.,Carter, L.,Bohn, A.,Bryan, C.M.,Fernandez-Velasco, D.A.,Stewart, L.,Dong, M.,Huang, X.,Jin, R.,Wilson, I.A.,Fuller, D.H.,Baker, D.; Massively parallel de novo protein design for targeted therapeutics.; Nature, 550:74-79, 2017; PubMed: 28953867; DOI: 10.1038/nature23912

Experimental method

X-RAY DIFFRACTION (1.799 Å)