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6CQ9

K2P2.1(TREK-1):ML402 complex

Replaces:  5VKP
Summary for 6CQ9
Entry DOI10.2210/pdb6cq9/pdb
Related6CQ8
DescriptorPotassium channel subfamily K member 2, POTASSIUM ION, N-[2-(4-chloro-2-methylphenoxy)ethyl]thiophene-2-carboxamide, ... (6 entities in total)
Functional Keywordstrek-1 ion channel k2p, transport protein
Biological sourceMus musculus (Mouse)
Total number of polymer chains2
Total formula weight72309.66
Authors
Lolicato, M.,Minor, D.L. (deposition date: 2018-03-14, release date: 2018-04-11, Last modification date: 2023-10-04)
Primary citationLolicato, M.,Arrigoni, C.,Mori, T.,Sekioka, Y.,Bryant, C.,Clark, K.A.,Minor, D.L.
K2P2.1 (TREK-1)-activator complexes reveal a cryptic selectivity filter binding site.
Nature, 547:364-368, 2017
Cited by
PubMed: 28693035
DOI: 10.1038/nature22988
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.8 Å)
Structure validation

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