5VCJ

Structure of alpha-galactosylphytosphingosine bound by CD1d and in complex with the Va14Vb8.2 TCR

Summary for 5VCJ

Entry DOI	10.2210/pdb5vcj/pdb
Descriptor	Antigen-presenting glycoprotein CD1d1, Beta-2-microglobulin, Chimeric TCR Valpha14/Jalpha18 chain (mouse variable domain, human constant domain), ... (8 entities in total)
Functional Keywords	immune system, antigen-presentation, tcr, mhc-fold
Biological source	Mus musculus (Mouse) More
Total number of polymer chains	4
Total formula weight	96611.09
Authors	Wang, J.,Zajonc, D.M. (deposition date: 2017-03-31, release date: 2018-04-04, Last modification date: 2023-10-04)
Primary citation	Compton, B.J.,Farrand, K.J.,Tang, C.W.,Osmond, T.L.,Speir, M.,Authier-Hall, A.,Wang, J.,Ferguson, P.M.,Chan, S.T.S.,Anderson, R.J.,Cooney, T.R.,Hayman, C.M.,Williams, G.M.,Brimble, M.A.,Brooks, C.R.,Yong, L.K.,Metelitsa, L.S.,Zajonc, D.M.,Godfrey, D.I.,Gasser, O.,Weinkove, R.,Painter, G.F.,Hermans, I.F. Enhancing T cell responses and tumour immunity by vaccination with peptides conjugated to a weak NKT cell agonist. Org. Biomol. Chem., 17:1225-1237, 2019 Cited by PubMed: 30656346 DOI: 10.1039/c8ob02982b PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.16 Å)

Structure validation