5VAG

Crystal structure of H7-specific antibody m826 in complex with the HA1 domain of hemagglutinin from H7N9 influenza virus

Summary for 5VAG

• Entry DOI: 10.2210/pdb5vag/pdb
• Descriptor: Hemagglutinin, Light chain of antibody m826, Heavy chain of antibody m826, ... (5 entities in total)
• Functional Keywords: hemagglutinin, h7n9, immune system
• Biological source: Influenza A virus; More
• Cellular location: Host apical cell membrane ; Single-pass type I membrane protein . Virion membrane ; Single-pass type I membrane protein : R4NN21
• Total number of polymer chains: 3
• Total formula weight: 85349.31

Authors

Song, H.,Ying, T.,Ji, X. (deposition date: 2017-03-26, release date: 2017-12-20, Last modification date: 2023-10-04)

• Primary citation: Yu, F.,Song, H.,Wu, Y.,Chang, S.Y.,Wang, L.,Li, W.,Hong, B.,Xia, S.,Wang, C.,Khurana, S.,Feng, Y.,Wang, Y.,Sun, Z.,He, B.,Hou, D.,Manischewitz, J.,King, L.R.,Song, Y.,Min, J.Y.,Golding, H.,Ji, X.,Lu, L.,Jiang, S.,Dimitrov, D.S.,Ying, T.; A Potent Germline-like Human Monoclonal Antibody Targets a pH-Sensitive Epitope on H7N9 Influenza Hemagglutinin.; Cell Host Microbe, 22:471-483.e5, 2017; PubMed: 28966056; DOI: 10.1016/j.chom.2017.08.011

Experimental method

X-RAY DIFFRACTION (1.9 Å)