5V3Q
Human GSTO1-1 complexed with ML175
Summary for 5V3Q
Entry DOI | 10.2210/pdb5v3q/pdb |
Related | 1EEM 3VLN 4IS0 |
Descriptor | Glutathione S-transferase omega-1, N-{3-[(2-chloro-acetyl)-(4-nitro-phenyl)-amino]-propyl}-2,2,2-trifluoro-acetamide, SULFATE ION, ... (4 entities in total) |
Functional Keywords | glutathione transferase, inhibitor, ml175, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Homo sapiens (Human) |
Cellular location | Cytoplasm, cytosol : P78417 |
Total number of polymer chains | 1 |
Total formula weight | 28159.68 |
Authors | Oakley, A.J. (deposition date: 2017-03-07, release date: 2017-12-20, Last modification date: 2023-10-04) |
Primary citation | Menon, D.,Innes, A.,Oakley, A.J.,Dahlstrom, J.E.,Jensen, L.M.,Brustle, A.,Tummala, P.,Rooke, M.,Casarotto, M.G.,Baell, J.B.,Nguyen, N.,Xie, Y.,Cuellar, M.,Strasser, J.,Dahlin, J.L.,Walters, M.A.,Burgio, G.,O'Neill, L.A.J.,Board, P.G. GSTO1-1 plays a pro-inflammatory role in models of inflammation, colitis and obesity. Sci Rep, 7:17832-17832, 2017 Cited by PubMed: 29259211DOI: 10.1038/s41598-017-17861-6 PDB entries with the same primary citation |
Experimental method |
Structure validation
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