5U0V
E. coli dihydropteroate synthase complexed with 6-methylamino-5-nitrosoisocytosine
Summary for 5U0V
Entry DOI | 10.2210/pdb5u0v/pdb |
Related | 5U0W 5U0X 5U0Y 5U0Z 5U10 5U11 5U12 5U13 5U14 |
Descriptor | Dihydropteroate synthase, 2-amino-6-(methylamino)-5-nitrosopyrimidin-4(3H)-one, SODIUM ION, ... (5 entities in total) |
Functional Keywords | e. coli, dhps, complex, pterin site, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) |
Total number of polymer chains | 2 |
Total formula weight | 62036.77 |
Authors | Peat, T.S.,Dennis, M.L.,Swarbrick, J.D. (deposition date: 2016-11-27, release date: 2017-12-06, Last modification date: 2023-10-04) |
Primary citation | Dennis, M.L.,Lee, M.D.,Harjani, J.R.,Ahmed, M.,DeBono, A.J.,Pitcher, N.P.,Wang, Z.C.,Chhabra, S.,Barlow, N.,Rahmani, R.,Cleary, B.,Dolezal, O.,Hattarki, M.,Aurelio, L.,Shonberg, J.,Graham, B.,Peat, T.S.,Baell, J.B.,Swarbrick, J.D. 8-Mercaptoguanine Derivatives as Inhibitors of Dihydropteroate Synthase. Chemistry, 24:1922-1930, 2018 Cited by PubMed: 29171692DOI: 10.1002/chem.201704730 PDB entries with the same primary citation |
Experimental method |
Structure validation
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