5TRN
Solution Structure of a DNA Dodecamer with 8-oxoguanine at the 4th position and 5-methylcytosine at the 9th position
Summary for 5TRN
Entry DOI | 10.2210/pdb5trn/pdb |
NMR Information | BMRB: 30198 |
Descriptor | DNA (5'-D(*CP*GP*CP*(8OG)P*AP*AP*TP*TP*(DMC)P*GP*CP*G)-3') (1 entity in total) |
Functional Keywords | drew-dickerson, dna, non-canonical, modified dna, methylated dna, epigenetics, cpg site |
Biological source | synthetic construct |
Total number of polymer chains | 2 |
Total formula weight | 7386.84 |
Authors | Hoppins, J.J.,Gruber, D.R.,Miears, H.L.,Endutkin, A.V.,Zharkov, D.O.,Smirnov, S.L. (deposition date: 2016-10-26, release date: 2017-06-28, Last modification date: 2024-05-01) |
Primary citation | Gruber, D.R.,Toner, J.J.,Miears, H.L.,Shernyukov, A.V.,Kiryutin, A.S.,Lomzov, A.A.,Endutkin, A.V.,Grin, I.R.,Petrova, D.V.,Kupryushkin, M.S.,Yurkovskaya, A.V.,Johnson, E.C.,Okon, M.,Bagryanskaya, E.G.,Zharkov, D.O.,Smirnov, S.L. Oxidative damage to epigenetically methylated sites affects DNA stability, dynamics and enzymatic demethylation. Nucleic Acids Res., 46:10827-10839, 2018 Cited by PubMed: 30289469DOI: 10.1093/nar/gky893 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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