5T2W
Structure of thymine DNA glycosylase bound to substrate analog 2'-F-5-formyl-dC
Summary for 5T2W
Entry DOI | 10.2210/pdb5t2w/pdb |
Descriptor | G/T mismatch-specific thymine DNA glycosylase, DNA (28-MER), DNA (27-MER), ... (4 entities in total) |
Functional Keywords | protein-dna complex, hydrolase-dna complex, hydrolase/dna |
Biological source | Homo sapiens (Human) More |
Cellular location | Nucleus : Q13569 |
Total number of polymer chains | 3 |
Total formula weight | 43118.09 |
Authors | Pidugu, L.S.,Pozharski, E.,Drohat, A.C. (deposition date: 2016-08-24, release date: 2016-11-09, Last modification date: 2023-10-04) |
Primary citation | Pidugu, L.S.,Flowers, J.W.,Coey, C.T.,Pozharski, E.,Greenberg, M.M.,Drohat, A.C. Structural Basis for Excision of 5-Formylcytosine by Thymine DNA Glycosylase. Biochemistry, 55:6205-6208, 2016 Cited by PubMed: 27805810DOI: 10.1021/acs.biochem.6b00982 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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