5S9C
PanDDA analysis group deposition -- Crystal Structure of PHIP in complex with Z198194396 synthetic derivative
Summary for 5S9C
Entry DOI | 10.2210/pdb5s9c/pdb |
Group deposition | PanDDA analysis group deposition (G_1002190) |
Descriptor | PH-interacting protein, N-(cyclopropylmethyl)-4-(thiophene-2-carbonyl)piperazine-1-carboxamide (3 entities in total) |
Functional Keywords | sgc - diamond i04-1 fragment screening, pandda, xchemexplorer, robotic chemistry, crystal soaking, reaction crudes, signaling protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 17921.24 |
Authors | Grosjean, H.,Aimon, A.,Hassel-Hart , S.,Krojer, T.,Talon, R.,Douangamath, A.,Koekemoer, L.,Biggin, P.C.,Spencer, J.,von Delft, F. (deposition date: 2021-01-22, release date: 2021-02-17, Last modification date: 2024-03-06) |
Primary citation | Grosjean, H.,Aimon, A.,Hart , S.,Krojer, T.,Talon, R.,Douangamath, A.,Koekemoer, L.,Biggin, P.C.,Spencer, J.,von Delft, F. Crystal Structures of the second bromodomain of Pleckstrin homology domain interacting protein (PHIP) in space group C2 soaked with crude reaction mixtures To Be Published, |
Experimental method |
Structure validation
Download full validation report![Download](/newweb/media/icons/dl.png)
![Download](/newweb/media/icons/dl.png)